HPLC/MS/MS & GC/MS ANALYSIS OF DRUGS & METABOLITES
ROCKY MOUNTAIN INSTRUMENTAL LABORATORIES provides chemical analysis of a large range of drug substances for clinical, pharmaceutical and forensic applications. We also provide quality assurance and quality control for diagnostics manufacturers.
The following is a portion of the drug substances for which we have valid methods. We test both clinical biosamples and pharmaceutical products using HPLC, HPLC/MS/MS, GC/MS, and FT/IR. Part of our expertise is the identification of drug degradants and metabolites using LC/MS/MS.
AMPHETAMINE ANALOGS
- Amphetamine
- Ephedrine
- Cathinone & Methcathinone
- Fenfluramine
- Methamphetamine
- MDMA
- MDA
- MDEA
- Methylphenidate (Ritalin)
- Phentermine
ANTI-BIOTICS
- Aminoglycosides (Gentamicin, Tobramycin, Amikacin)
- Amoxicillin
- Cephapirin and Desacetyl-cephapirin
- Ceftiofur and metabolites
- Erythromycin
- Fluoroquinolones
- Tetracyclines
ANTI-CANCER AGENTS
- Paclitaxel (TAXOL)
- Doxorubicin
- Epirubicin
- Daunorubicin
ANTI-REJECTION AGENTS
BARBITURATES & ANALOGS
- Amobarbital
- Butalbital
- Glutethimide
- Pentobarbital
- Phenobarbital
- PEMA
- Primidone
- Secobarbital
- Thiopental
- Phenytoin (Dilantin) & Metabolites.
- Phensuximide & Methsuximide
BENZODIAZEPINES & HYPNOTICS
- Alprazolam & a-OH-Alprazolam
- Bromazepam
- Clonazepam & metabolite
- Diazepam & Nordiazepam
- Halazepam
- Lorazepam
- Lormetazepam
- Midazolam & metabolite
- Oxazepam
- Temazepam
- Flunitrazepam & 7-amino-FNP
- Flurazepam & Desalkyl-FZ
- Zolpidem
- Zopiclone
- Zaleplon
COCAINOIDS
- Benzoyl ecgonine
- Cocaine
- Cocaethylene
- Cinnamoyl cocaine
- Ecgonine methyl ester
- Ecgonine ethyl ester
OPIATES & ANALGESICS
- Acetaminophen
- Acetyl-Morphine (6-MAM)
- Buprenorphine & Metabolite
- Codeine
- Ibuprofen
- Fentanyl & metabolites
- Alfentanil
- Carfentanil
- Sufentanil
- Remifentanil
- Hydrocodone
- Hydromorphone
- Meperidine & Nor-meperidine
- Methadone
EDDP
- Morphine
- Oxycodone & Noroxycodone
- Oxymorphone & Noroxymorphone
- Propoxyphene & Norpropoxyphene
- Etorphine (M-99)
- Salicylate
- Tramadol & metabolite
PSYCHOACTIVES
- Acepromazine & analogs
- LSD & Iso-LSD
- PCP
- JWH-018 and similar compounds (Spice)
- Carisoprodol & Meprobamate
- Chantix (Varenicline)
- GHB, GBL & 1,4-BD
- Tryptamines (many)
- Fluoxetine & Nor-fluoxetine
- Paroxetine
- Ketamine
- Methaqualone
- Sertraline
- Selegiline
- Fluvoxamine
- Olanzapine & metabolite
- Trihexphenidyl (Artane)
- Trazodone
- THC, THC-OH, THC-A
- Xylazine (Rompun)
TRICYCLICS
- Amitriptyline & Nortriptyline
- Imipramine & Desipramine
- Clomipramine
- Doxepin & Nor-doxepin
- Cyclobenzaprine & metabolite
MISCELLANEOUS
- Digoxin
- Digitoxin
- Gitoxin
- Cimetidine
- Caffeine
- HCG (Human Chorionic Gonadotrophin by LCMSMS)
- Theophylline
- Nicotine
- Cotinine
- Gabapentin
- Diphenhydramine
- Zidovudine (AZT) & AMT
- Diphenylbutazone
- Fipronil
Rocky Mountain Instrumental Laboratories provides LCMSMS and GCMS analysis of a very large variety of pharmaceutical agents. If a drug of interest is not on the above list, please ask. RML develops analytical methods for new entities and their metabolites.
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Updated: 29 July 2010